My research focuses on the development and application of nano-biosensors for detection and characterization of chemical and biological targets in foods and in environmental and medical samples.
In our work we utilize nano-sized particles to develop specific molecular probes that can interact with a variety of targets with high affinity. The resulting detection method- ology offers highly accurate and sensitive responses to trace amounts of targets in complex environments and samples. We focus on developing portable devices that can be deployed in-field for fast detection. The techniques developed in our lab can be widely applied to address biosensing needs for food and biosafety, environmental quality, and biomedical diagnosis.
Key Environmental Science Publications
Xiao, N., Chenxu Yu, "Rapid-response and Highly Sensitive Non-crosslinking Colorimetric Nitrite Sensor Using 4-aminothiophenol Modified Gold Nanorods," Analytical Chemistry, 82 (9), 3659–3663, 2010
Wang, Q., N. Xiao and Chenxu Yu, "Detection and identification of microorganisms in mixed cultures by nanoparticle enhanced FTIR spectroscopy and chemometrics," ASABE transaction, 53(3): 999-1006, 2010
Chenxu Yu, J. Irudayaraj, "Quantitative Evaluation of Sensitivity and Selectivity of Multiplex NanoSPR Biosensor Assays," Biophysical Journal 2007 93(10): 3684-3692
Sun, L., Chenxu Yu, J. Irudayaraj, "Surface-Enhanced Raman Scattering Based Non fluorescent Probe for Multiplex DNA Detection," Analytical Chemistry 79 (11): 3981 -3988, 2007